● TIER 3 — Information onlyGRADE B- (old Russian clinical use); harm data strongNootropic / neuro peptides
Phenibut (β-phenyl-GABA)
Origin: USSR/Russia (1960s). Citations verified: yes. 3 human study record(s) in the FitClinicMD studies database.
GOALS · Sleep · Cognition
FDA status
Not an FDA-approved product
Compounding (503A/503B)
Status varies — see notes
DEA
Not listed as controlled
WADA (sport)
Not specified
Mechanism
GABA-B (some GABA-A) agonist, baclofen analog 1.
Human evidence · 3
CDC MMWR 2020 poison center exposures.
2020other/unspecified
Systematic review of phenibut toxicity and withdrawal (J Addict Med).
systematic review
Phenibut withdrawal treatment review (J Clin Pharmacol).
review (narrative)
Reference only. This page summarizes publicly available regulatory and research information about Phenibut (β-phenyl-GABA). It is not a prescription, an endorsement, or an offer to dispense, and regulatory status can change. Clinicians should verify current status before prescribing or compounding.